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BMCBI
2010
202views more  BMCBI 2010»
13 years 6 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2006
122views more  BMCBI 2006»
13 years 5 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
CMSB
2009
Springer
13 years 9 months ago
Control Strategies for the Regulation of the Eukaryotic Heat Shock Response
Abstract. Elevated temperatures cause proteins in living cells to misfold. They start forming larger and larger aggregates that can eventually lead to the cell's death. The he...
Elena Czeizler, Eugen Czeizler, Ralph-Johan Back, ...
BMCBI
2008
138views more  BMCBI 2008»
13 years 6 months ago
CASCADE: a novel quasi all paths-based network analysis algorithm for clustering biological interactions
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2008
120views more  BMCBI 2008»
13 years 6 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...