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BIOINFORMATICS
2011
8 years 7 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
VLDB
2001
ACM
109views Database» more  VLDB 2001»
9 years 8 months ago
Mining Multi-Dimensional Constrained Gradients in Data Cubes
Constrained gradient analysis (similar to the “cubegrade” problem posed by Imielinski, et al. [9]) is to extract pairs of similar cell characteristics associated with big chan...
Guozhu Dong, Jiawei Han, Joyce M. W. Lam, Jian Pei...
GECCO
2007
Springer
168views Optimization» more  GECCO 2007»
9 years 10 months ago
Genetic multi-step search in interpolation and extrapolation domain
The deterministic Multi-step Crossover Fusion (dMSXF) is an improved crossover method of MSXF which is a promising method of JSP, and it shows high availability in TSP. Both of th...
Yoshiko Hanada, Tomoyuki Hiroyasu, Mitsunori Miki
BMCBI
2010
201views more  BMCBI 2010»
9 years 3 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
BMCBI
2006
174views more  BMCBI 2006»
9 years 3 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
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