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BMCBI
2005
141views more  BMCBI 2005»
13 years 4 months ago
A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
Background: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligan...
Nikolaos G. Sgourakis, Pantelis G. Bagos, Panagiot...
BMCBI
2007
130views more  BMCBI 2007»
13 years 4 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...
BMCBI
2007
142views more  BMCBI 2007»
13 years 4 months ago
Support Vector Machine-based method for predicting subcellular localization of mycobacterial proteins using evolutionary informa
Background: In past number of methods have been developed for predicting subcellular location of eukaryotic, prokaryotic (Gram-negative and Gram-positive bacteria) and human prote...
Mamoon Rashid, Sudipto Saha, Gajendra P. S. Raghav...