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» A model-based approach to selection of tag SNPs
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BMCBI
2006
116views more  BMCBI 2006»
13 years 3 months ago
A model-based approach to selection of tag SNPs
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
Pierre Nicolas, Fengzhu Sun, Lei M. Li
CPM
2004
Springer
145views Combinatorics» more  CPM 2004»
13 years 9 months ago
Computational Problems in Perfect Phylogeny Haplotyping: Xor-Genotypes and Tag SNPs
The perfect phylogeny model for haplotype evolution has been successfully applied to haplotype resolution from genotype data. In this study we explore the application of the perfe...
Tamar Barzuza, Jacques S. Beckmann, Ron Shamir, It...
BMCBI
2005
94views more  BMCBI 2005»
13 years 3 months ago
A method for finding single-nucleotide polymorphisms with allele frequencies in sequences of deep coverage
Background: The allele frequencies of single-nucleotide polymorphisms (SNPs) are needed to select an optimal subset of common SNPs for use in association studies. Sequence-based m...
Jianmin Wang, Xiaoqiu Huang
BMCBI
2006
135views more  BMCBI 2006»
13 years 3 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
13 years 9 months ago
Minimal Marker Sets to Discriminate Among Seedlines
Raising seeds for biological experiments is prone to error; a careful experimenter will test in the lab to verify that plants are of the intended strain. Choosing a minimal set of...
Thomas C. Hudson, Ann E. Stapleton, Amy M. Curley