7 search results - page 1 / 2 » A model-based optimization framework for the inference of re... |
BMCBI
2007
13 years 4 months ago
2007
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
BMCBI
2005
13 years 4 months ago
2005
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
BMCBI
2010
13 years 4 months ago
2010
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
BMCBI
2007
13 years 4 months ago
2007
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
BMCBI
2007
13 years 4 months ago
2007
Background: The regulation of gene expression is achieved through gene regulatory networks (GRNs) in which collections of genes interact with one another and other substances in a...