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BMCBI
2008
84views more  BMCBI 2008»
13 years 5 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
BMCBI
2006
108views more  BMCBI 2006»
13 years 4 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg