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» A novel ab-initio genetic-based approach for protein folding...
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BMCBI
2008
57views more  BMCBI 2008»
13 years 5 months ago
A novel method for high accuracy sumoylation site prediction from protein sequences
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
Jialin Xu, Yun He, Boqin Qiang, Jiangang Yuan, Xia...
BMCBI
2007
93views more  BMCBI 2007»
13 years 5 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
ICLP
2004
Springer
13 years 10 months ago
Protein Folding Simulation in CCP
A protein is identified by a finite sequence of aminoacids, each of them chosen from a set of 20 elements. The Protein Structure Prediction Problem is the problem of predicting t...
Alessandro Dal Palù, Agostino Dovier, Feder...
GECCO
2007
Springer
211views Optimization» more  GECCO 2007»
13 years 11 months ago
An extremal optimization search method for the protein folding problem: the go-model example
The protein folding problem consists of predicting the functional (native) structure of the protein given its linear sequence of amino acids. Despite extensive progress made in un...
Alena Shmygelska
BMCBI
2007
168views more  BMCBI 2007»
13 years 5 months ago
Benchmarking consensus model quality assessment for protein fold recognition
Background: Selecting the highest quality 3D model of a protein structure from a number of alternatives remains an important challenge in the field of structural bioinformatics. M...
Liam J. McGuffin