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BMCBI
2006
172views more  BMCBI 2006»
13 years 5 months ago
A novel scoring schema for peptide identification by searching protein sequence databases using tandem mass spectrometry data
Background: Tandem mass spectrometry (MS/MS) is a powerful tool for protein identification. Although great efforts have been made in scoring the correlation between tandem mass sp...
Zhuo Zhang, Shiwei Sun, Xiaopeng Zhu, Suhua Chang,...
BMCBI
2007
149views more  BMCBI 2007»
13 years 4 months ago
SAMPI: Protein Identification with Mass Spectra Alignments
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
Hans-Michael Kaltenbach, Andreas Wilke, Sebastian ...
BMCBI
2010
152views more  BMCBI 2010»
13 years 5 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...
DATESO
2010
169views Database» more  DATESO 2010»
13 years 2 months ago
Parametrised Hausdorff Distance as a Non-Metric Similarity Model for Tandem Mass Spectrometry
Abstract. Tandem mass spectrometry is a widely used method for protein and peptide sequences identification. Since the mass spectra contain up to 80% of noise and many other inaccu...
Jiri Novák, David Hoksza
BMCBI
2007
91views more  BMCBI 2007»
13 years 5 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas