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    CSDA
    2007
    151views more  CSDA 2007»
    Robust semiparametric mixing for detecting differentially expressed genes in microarray experiments
    13 years 5 months ago
    Robust semiparametric mixing for detecting differentially expressed genes in microarray experiments
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    An important goal of microarray studies is the detection of genes that show significant changes in observed expressions when two or more classes of biological samples such as tre...
    Marco Alfò, Alessio Farcomeni, Luca Tardell...
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    BMCBI
    2010
    115views more  BMCBI 2010»
    Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
    13 years 5 months ago
    Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
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    Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
    Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
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    BMCBI
    2005
    135views more  BMCBI 2005»
    A robust two-way semi-linear model for normalization of cDNA microarray data
    13 years 5 months ago
    A robust two-way semi-linear model for normalization of cDNA microarray data
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    Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
    Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
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    BMCBI
    2008
    124views more  BMCBI 2008»
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
    13 years 5 months ago
    A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
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    Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
    Huanying Ge, Chao Cheng, Lei M. Li
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    BMCBI
    2007
    86views more  BMCBI 2007»
    Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
    13 years 5 months ago
    Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
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    Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
    William O. Ward, Carol D. Swartz, Steffen Porwolli...
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