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» A replica exchange Monte Carlo algorithm for protein folding...
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BMCBI
2007
216views more  BMCBI 2007»
13 years 4 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
AI
2003
Springer
13 years 9 months ago
An Improved Ant Colony Optimisation Algorithm for the 2D HP Protein Folding Problem
The prediction of a protein’s structure from its amino-acid sequence is one of the most important problems in computational biology. In the current focus on a widely studied abst...
Alena Shmygelska, Holger H. Hoos
GECCO
2007
Springer
211views Optimization» more  GECCO 2007»
13 years 10 months ago
An extremal optimization search method for the protein folding problem: the go-model example
The protein folding problem consists of predicting the functional (native) structure of the protein given its linear sequence of amino acids. Despite extensive progress made in un...
Alena Shmygelska
BMCBI
2005
152views more  BMCBI 2005»
13 years 4 months ago
An ant colony optimisation algorithm for the 2D and 3D hydrophobic polar protein folding problem
Background: The protein folding problem is a fundamental problems in computational molecular biology and biochemical physics. Various optimisation methods have been applied to for...
Alena Shmygelska, Holger H. Hoos
BMCBI
2007
143views more  BMCBI 2007»
13 years 4 months ago
An adaptive bin framework search method for a beta-sheet protein homopolymer model
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
Alena Shmygelska, Holger H. Hoos