Sciweavers

11 search results - page 1 / 3
» A scoring matrix approach to detecting miRNA target sites
Sort
View
ALMOB
2008
124views more  ALMOB 2008»
13 years 4 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
BMCBI
2007
165views more  BMCBI 2007»
13 years 4 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BMCBI
2010
104views more  BMCBI 2010»
13 years 4 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
RECOMB
2007
Springer
14 years 4 months ago
A Feature-Based Approach to Modeling Protein-DNA Interactions
Transcription factor (TF) binding to its DNA target site is a fundamental regulatory interaction. The most common model used to represent TF binding specificities is a position spe...
Eilon Sharon, Eran Segal
IPPS
2008
IEEE
13 years 11 months ago
Adaptive Locality-Effective Kernel Machine for protein phosphorylation site prediction
In this study, we propose a new machine learning model namely, Adaptive Locality-Effective Kernel Machine (Adaptive-LEKM) for protein phosphorylation site prediction. Adaptive-LEK...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...