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» A stable gene selection in microarray data analysis
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BMCBI
2005
169views more  BMCBI 2005»
13 years 5 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...
TKDE
1998
122views more  TKDE 1998»
13 years 5 months ago
The Design and Implementation of Seeded Trees: An Efficient Method for Spatial Joins
—Existing methods for spatial joins require pre-existing spatial indices or other precomputation, but such approaches are inefficient and limited in generality. Operand data sets...
Ming-Ling Lo, Chinya V. Ravishankar
BMCBI
2007
145views more  BMCBI 2007»
13 years 5 months ago
The utility of MAS5 expression summary and detection call algorithms
Background: Used alone, the MAS5.0 algorithm for generating expression summaries has been criticized for high False Positive rates resulting from exaggerated variance at low inten...
Stuart D. Pepper, Emma K. Saunders, Laura E. Edwar...
BMCBI
2004
114views more  BMCBI 2004»
13 years 5 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...