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» A statistical approach for array CGH data analysis
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BMCBI
2005
104views more  BMCBI 2005»
13 years 3 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
CDC
2008
IEEE
157views Control Systems» more  CDC 2008»
13 years 3 months ago
A hidden Markov filtering approach to multiple change-point models
We describe a hidden Markov modeling approach to multiple change-points that has attractive computational and statistical properties. This approach yields explicit recursive filter...
Tze Leung Lai, Haipeng Xing
BMCBI
2007
180views more  BMCBI 2007»
13 years 3 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
BMCBI
2010
101views more  BMCBI 2010»
13 years 3 months ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
BIBE
2007
IEEE
133views Bioinformatics» more  BIBE 2007»
13 years 10 months ago
Denoising of Array-Based DNA Copy Number Data Using The Dual-tree Complex Wavelet Transform
—Array-based comparative genomic hybridization (array CGH) is a highly efficient technique, allowing the simultaneous measurement of genomic DNA copy number at hundreds or thous...
Nha Nguyen, Heng Huang, Soontorn Oraintara, Yuhang...