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» A statistical approach for array CGH data analysis
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BMCBI
2007
147views more  BMCBI 2007»
13 years 4 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
BMCBI
2010
133views more  BMCBI 2010»
13 years 4 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
SADM
2008
178views more  SADM 2008»
13 years 4 months ago
Fast Projection-Based Methods for the Least Squares Nonnegative Matrix Approximation Problem
: Nonnegative matrix approximation (NNMA) is a popular matrix decomposition technique that has proven to be useful across a diverse variety of fields with applications ranging from...
Dongmin Kim, Suvrit Sra, Inderjit S. Dhillon