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BIB
2008
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13 years 4 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
CMSB
2007
Springer
13 years 11 months ago
A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets
We give a description of a Petri net-based framework for modelling and analysing biochemical pathways, which unifies the qualitative, stochastic and continuous paradigms. Each per...
David Gilbert, Monika Heiner, Sebastian Lehrack
CMSB
2003
Springer
13 years 10 months ago
An Overview of Data Models for the Analysis of Biochemical Pathways
Biochemical pathways such as metabolic, regulatory or signal tranduction pathways can be viewed as interconnected processes forming an intricate network of functional and physical...
Yves Deville, David Gilbert, Jacques van Helden, S...
CMSB
2008
Springer
13 years 6 months ago
A Model Checking Approach to the Parameter Estimation of Biochemical Pathways
Model checking has historically been an important tool to verify models of a wide variety of systems. Typically a model has to exhibit certain properties to be classed `acceptable&...
Robin Donaldson, David Gilbert
APN
2006
Springer
13 years 6 months ago
From Petri Nets to Differential Equations - An Integrative Approach for Biochemical Network Analysis
Abstract. We report on the results of an investigation into the integration of Petri nets and ordinary differential equations (ODEs) for the modelling and analysis of biochemical n...
David Gilbert, Monika Heiner