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AAAI
2004
13 years 6 months ago
Space-Efficient Memory-Based Heuristics
A memory-based heuristic is a heuristic function that is stored in a lookup table. Very accurate heuristics have been created by building very large lookup tables, sometimes calle...
Rong Zhou, Eric A. Hansen
BMCBI
2007
179views more  BMCBI 2007»
13 years 5 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
BMCBI
2006
166views more  BMCBI 2006»
13 years 5 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2008
130views more  BMCBI 2008»
13 years 5 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2006
148views more  BMCBI 2006»
13 years 5 months ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower