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» Accurate detection of very sparse sequence motifs
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BMCBI
2004
158views more  BMCBI 2004»
13 years 5 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2007
247views more  BMCBI 2007»
13 years 5 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2004
229views more  BMCBI 2004»
13 years 5 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
IMSCCS
2006
IEEE
13 years 11 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
BMCBI
2011
12 years 9 months ago
Binding Site Prediction for Protein-Protein Interactions and Novel Motif Discovery using Re-occurring Polypeptide Sequences
Background: While there are many methods for predicting protein-protein interaction, very few can determine the specific site of interaction on each protein. Characterization of t...
Adam Amos-Binks, Catalin Patulea, Sylvain Pitre, A...