5 search results - page 1 / 1 » Accurate statistics for local sequence alignment with positi... |
BMCBI
2011
12 years 11 months ago
2011
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
CIKM
2008
Springer
13 years 6 months ago
2008
Springer
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
WABI
2009
Springer
13 years 11 months ago
2009
Springer
We present a novel dynamic programming framework that allows one to compute tight upper bounds for the p-values of gapped local alignments in pseudo–polynomial time. Our algorith...
BMCBI
2007
13 years 4 months ago
2007
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
BMCBI
2010
13 years 4 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...