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BMCBI
2006
169views more  BMCBI 2006»
13 years 6 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
JMLR
2008
209views more  JMLR 2008»
13 years 6 months ago
Bayesian Inference and Optimal Design for the Sparse Linear Model
The linear model with sparsity-favouring prior on the coefficients has important applications in many different domains. In machine learning, most methods to date search for maxim...
Matthias W. Seeger
BMCBI
2004
117views more  BMCBI 2004»
13 years 6 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
BMCBI
2010
171views more  BMCBI 2010»
13 years 6 months ago
PyMix - The Python mixture package - a tool for clustering of heterogeneous biological data
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...
BMCBI
2010
155views more  BMCBI 2010»
13 years 6 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe