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» Adaptive Modeling of Biochemical Pathways
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BMCBI
2005
140views more  BMCBI 2005»
13 years 6 months ago
Dissecting systems-wide data using mixture models: application to identify affected cellular processes
Background: Functional analysis of data from genome-scale experiments, such as microarrays, requires an extensive selection of differentially expressed genes. Under many condition...
J. Peter Svensson, Renée X. de Menezes, Ing...
BMCBI
2010
109views more  BMCBI 2010»
13 years 6 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
CHI
2007
ACM
14 years 6 months ago
Citizen communications in crisis: anticipating a future of ICT-supported public participation
Recent world-wide crisis events have drawn new attention to the role information communication technology (ICT) can play in warning and response activities. Drawing on disaster so...
Leysia Palen, Sophia B. Liu
SAC
2009
ACM
14 years 1 months ago
Capturing truthiness: mining truth tables in binary datasets
We introduce a new data mining problem: mining truth tables in binary datasets. Given a matrix of objects and the properties they satisfy, a truth table identifies a subset of pr...
Clifford Conley Owens III, T. M. Murali, Naren Ram...
BMCBI
2006
161views more  BMCBI 2006»
13 years 6 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen