Background: Information obtained by DNA microarray technology gives a rough snapshot of the transcriptome state, i.e., the expression level of all the genes expressed in a cell po...
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
Background: Network Component Analysis (NCA) has shown its effectiveness in discovering regulators and inferring transcription factor activities (TFAs) when both microarray data a...
Chen Wang, Jianhua Xuan, Li Chen, Po Zhao, Yue Wan...
Background: Signal transduction is one of the most important biological processes by which cells convert an external signal into a response. Novel computational approaches to mapp...