444 search results - page 2 / 89 » Algorithms for Association Study Design Using a Generalized ... |
BMCBI
2004
13 years 5 months ago
2004
Background: In population-based studies, it is generally recognized that single nucleotide polymorphism (SNP) markers are not independent. Rather, they are carried by haplotypes, ...
BMCBI
2008
13 years 5 months ago
2008
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
BMCBI
2010
13 years 2 months ago
2010
Background: Genomewide association studies have resulted in a great many genomic regions that are likely to harbor disease genes. Thorough interrogation of these specific regions ...
JCB
2006
13 years 5 months ago
2006
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
BIOINFORMATICS
2007
13 years 5 months ago
2007
In the context of disease association studies, haplotype frequencies are usually estimated from genotype data. In order to reduce genotyping costs, one can estimate the haplotype ...