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BMCBI
2006
112views more  BMCBI 2006»
13 years 4 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
JCSS
2007
116views more  JCSS 2007»
13 years 4 months ago
The most probable annotation problem in HMMs and its application to bioinformatics
Hidden Markov models (HMMs) are often used for biological sequence annotation. Each sequence feature is represented by a collection of states with the same label. In annotating a ...
Brona Brejová, Daniel G. Brown 0001, Tom&aa...
BMCBI
2010
117views more  BMCBI 2010»
13 years 5 months ago
New decoding algorithms for Hidden Markov Models using distance measures on labellings
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
Daniel G. Brown 0001, Jakub Truszkowski
CEC
2005
IEEE
13 years 10 months ago
Evolving hidden Markov models for protein secondary structure prediction
New results are presented for the prediction of secondary structure information for protein sequences using Hidden Markov Models (HMMs) evolved using a Genetic Algorithm (GA). We a...
Kyoung-Jae Won, Thomas Hamelryck, Adam Prügel...
CVIU
2008
180views more  CVIU 2008»
13 years 5 months ago
Topology cuts: A novel min-cut/max-flow algorithm for topology preserving segmentation in N-D images
Topology is an important prior in many image segmentation tasks. In this paper, we design and implement a novel graph-based min-cut/max-flow algorithm that incorporates topology p...
Yun Zeng, Dimitris Samaras, Wei Chen, Qunsheng Pen...