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CIAC
2010
Springer
194views Algorithms» more  CIAC 2010»
13 years 9 months ago
An Algorithmic Framework for Motif Discovery Problems in Weighted Sequences
A weighted sequence is a string in which a set of characters may appear at each position with respective probabilities of occurrence. A common task is to locate a given motif in a ...
Hui Zhang, Qing Guo, Costas S. Iliopoulos
BMCBI
2010
153views more  BMCBI 2010»
13 years 4 months ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2007
190views more  BMCBI 2007»
13 years 4 months ago
Discriminative motif discovery in DNA and protein sequences using the DEME algorithm
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
Emma Redhead, Timothy L. Bailey
SAC
2004
ACM
13 years 10 months ago
Guiding motif discovery by iterative pattern refinement
In this paper, we demonstrate that the performance of a motif discovery algorithm can be significantly improved by embedding it into a novel framework that effectively guides the ...
Zhiping Wang, Mehmet M. Dalkilic, Sun Kim
BMCBI
2007
145views more  BMCBI 2007»
13 years 4 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...