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» An Entropic Estimator for Structure Discovery
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BMCBI
2007
227views more  BMCBI 2007»
13 years 6 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
CIKM
2008
Springer
13 years 8 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang
BMCBI
2006
103views more  BMCBI 2006»
13 years 6 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2007
131views more  BMCBI 2007»
13 years 6 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
ICDM
2007
IEEE
183views Data Mining» more  ICDM 2007»
14 years 14 days ago
Depth-Based Novelty Detection and Its Application to Taxonomic Research
It is estimated that less than 10 percent of the world’s species have been described, yet species are being lost daily due to human destruction of natural habitats. The job of d...
Yixin Chen, Henry L. Bart Jr., Xin Dang, Hanxiang ...