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BMCBI
2010
88views more  BMCBI 2010»
13 years 4 months ago
FastTagger: an efficient algorithm for genome-wide tag SNP selection using multi-marker linkage disequilibrium
Background: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic ...
Guimei Liu, Yue Wang, Limsoon Wong
BMCBI
2011
12 years 11 months ago
SNPPicker: High quality tag SNP selection across multiple populations
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
BMCBI
2008
119views more  BMCBI 2008»
13 years 4 months ago
Snagger: A user-friendly program for incorporating additional information for tagSNP selection
Background: There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not account f...
Christopher K. Edlund, Won H. Lee, Dalin Li, David...
JCB
2006
123views more  JCB 2006»
13 years 4 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange