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IJDMB
2006
90views more  IJDMB 2006»
13 years 4 months ago
An efficient motif discovery algorithm with unknown motif length and number of binding sites
: Most motif discovery algorithms from DNA sequences require the motif's length as input. Styczynski et al. introduced the Extended (l,d)-Motif Problem (EMP) where the motif&#...
Henry C. M. Leung, Francis Y. L. Chin
TSP
2008
91views more  TSP 2008»
13 years 4 months ago
A Sequential Monte Carlo Method for Motif Discovery
We propose a sequential Monte Carlo (SMC)-based motif discovery algorithm that can efficiently detect motifs in datasets containing a large number of sequences. The statistical di...
Kuo-ching Liang, Xiaodong Wang, Dimitris Anastassi...
BMCBI
2007
141views more  BMCBI 2007»
13 years 4 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2007
179views more  BMCBI 2007»
13 years 4 months ago
rMotifGen: random motif generator for DNA and protein sequences
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
Eric C. Rouchka, C. Timothy Hardin
GECCO
2005
Springer
140views Optimization» more  GECCO 2005»
13 years 10 months ago
MDGA: motif discovery using a genetic algorithm
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
Dongsheng Che, Yinglei Song, Khaled Rasheed