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ALMOB
2006
138views more  ALMOB 2006»
13 years 3 months ago
An enhanced RNA alignment benchmark for sequence alignment programs
Background: The performance of alignment programs is traditionally tested on sets of protein sequences, of which a reference alignment is known. Conclusions drawn from such protei...
Andreas Wilm, Indra Mainz, Gerhard Steger
BMCBI
2008
106views more  BMCBI 2008»
13 years 3 months ago
Searching for evolutionary distant RNA homologs within genomic sequences using partition function posterior probabilities
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...
BMCBI
2008
140views more  BMCBI 2008»
13 years 3 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh
NAR
2010
107views more  NAR 2010»
12 years 10 months ago
PLAST-ncRNA: Partition function Local Alignment Search Tool for non-coding RNA sequences
Alignment-based programs are valuable tools for finding potential homologs in genome sequences. Previously, it has been shown that partition function posterior probabilities attun...
Satish Chikkagoudar, Dennis R. Livesay, Usman Rosh...
COMPLIFE
2005
Springer
13 years 9 months ago
Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization
During the last few years new functionalities of RNA have been discovered, renewing the need for computational tools for their analysis. To this respect, multiple sequence alignmen...
Markus Bauer, Gunnar W. Klau, Knut Reinert