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SNPD
2004
13 years 6 months ago
Using extended phylogenetc profiles and support vector machines for protein family classification
We proposed a new approach to compare profiles when the correlations among attributes can be represented as a tree. To account for these correlations, the profile is extended with...
Kishore Narra, Li Liao
BMCBI
2010
153views more  BMCBI 2010»
13 years 4 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2007
105views more  BMCBI 2007»
13 years 4 months ago
HoxPred: automated classification of Hox proteins using combinations of generalised profiles
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
Morgane Thomas-Chollier, Luc Leyns, Valérie...
BMCBI
2008
170views more  BMCBI 2008»
13 years 4 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2006
116views more  BMCBI 2006»
13 years 4 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi