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    BMCBI
    2010
    84views more  BMCBI 2010»
    An integrated analysis of molecular aberrations in NCI-60 cell lines
    13 years 4 months ago
    An integrated analysis of molecular aberrations in NCI-60 cell lines
    Download  www.stat.sinica.edu.tw
    Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
    Chen-Hsiang Yeang
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    BMCBI
    2010
    133views more  BMCBI 2010»
    Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
    13 years 4 months ago
    Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
    Download  www.biomedcentral.com
    Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
    Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
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    BMCBI
    2005
    144views more  BMCBI 2005»
    Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
    13 years 4 months ago
    Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
    Download  www.biomedcentral.com
    Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
    Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...
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    BMCBI
    2010
    131views more  BMCBI 2010»
    Prediction of epigenetically regulated genes in breast cancer cell lines
    13 years 4 months ago
    Prediction of epigenetically regulated genes in breast cancer cell lines
    Download  www.biomedcentral.com
    Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
    Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
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    BMCBI
    2011
    229views Artificial Intelligence» more  BMCBI 2011»
    The PathOlogist: An Automated Tool for Pathway-Centric Analysis
    12 years 11 months ago
    The PathOlogist: An Automated Tool for Pathway-Centric Analysis
    Download  www.biomedcentral.com
    Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
    Sharon I. Greenblum, Sol Efroni, Carl F. Schaefer,...
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