This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of s...
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
This paper presents the software architecture and implementation of the problem solving environment (PSE) PELLPACK for modeling physical objects described by partial differential ...
Elias N. Houstis, John R. Rice, Sanjiva Weerawaran...