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» Analysis of DNA strand-specific differential expression with...
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BMCBI
2004
124views more  BMCBI 2004»
13 years 5 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2005
113views more  BMCBI 2005»
13 years 5 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
BMCBI
2006
160views more  BMCBI 2006»
13 years 5 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
BMCBI
2006
115views more  BMCBI 2006»
13 years 5 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2006
103views more  BMCBI 2006»
13 years 5 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux