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BMCBI
2008
151views more  BMCBI 2008»
13 years 4 months ago
Application of the Linux cluster for exhaustive window haplotype analysis using the FBAT and Unphased programs
Background: Genetic association studies have been used to map disease-causing genes. A newly introduced statistical method, called exhaustive haplotype association study, analyzes...
Hiroyuki Mishima, Andrew C. Lidral, Jun Ni
BMCBI
2010
124views more  BMCBI 2010»
13 years 4 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...
BMCBI
2011
12 years 8 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
BMCBI
2010
151views more  BMCBI 2010»
13 years 4 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...