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BMCBI
2006
117views more  BMCBI 2006»
13 years 4 months ago
Analysis of gene expression changes in relation to toxicity and tumorigenesis in the livers of Big Blue transgenic rats fed comf
Background: Comfrey is consumed by humans as a vegetable and a tea, and has been used as an herbal medicine for more than 2000 years. Comfrey, however, is hepatotoxic in livestock...
Nan Mei, Lei Guo, Lu Zhang 0013, Leming M. Shi, Yo...
BMCBI
2007
101views more  BMCBI 2007»
13 years 4 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BMCBI
2007
126views more  BMCBI 2007»
13 years 4 months ago
Comparison of gene expression profiles altered by comfrey and riddelliine in rat liver
Background: Comfrey (Symphytum officinale) is a perennial plant and has been consumed by humans as a vegetable, a tea and an herbal medicine for more than 2000 years. It, however,...
Lei Guo, Nan Mei, Stacey L. Dial, James C. Fuscoe,...