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» Analysis of variance components in gene expression data
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BMCBI
2007
138views more  BMCBI 2007»
13 years 5 months ago
A full Bayesian hierarchical mixture model for the variance of gene differential expression
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...
Samuel O. M. Manda, Rebecca E. Walls, Mark S. Gilt...
BMCBI
2006
151views more  BMCBI 2006»
13 years 5 months ago
Modeling Sage data with a truncated gamma-Poisson model
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
Helene H. Thygesen, Aeilko H. Zwinderman
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 2 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
CSDA
2006
81views more  CSDA 2006»
13 years 5 months ago
A recursive approach to detect multivariable conditional variance components and conditional random effects
A complex trait like crop yield is determined by its component traits. Multivariable conditional analysis in a general mixed linear model is helpful in dissecting the gene express...
Jixiang Wu, Dongfeng Wu, Johnie N. Jenkins Jr., Ja...
BMCBI
2010
243views more  BMCBI 2010»
13 years 5 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...