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BIOINFORMATICS
2011
12 years 8 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
BMCBI
2011
12 years 8 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...
AIME
2009
Springer
13 years 9 months ago
Prediction of Mechanical Lung Parameters Using Gaussian Process Models
Abstract. Mechanical ventilation can cause severe lung damage by inadequate adjustment of the ventilator. We introduce a Machine Learning approach to predict the pressure-dependent...
Steven Ganzert, Stefan Kramer, Knut Möller, D...