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BMCBI
2008
117views more  BMCBI 2008»
13 years 4 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
13 years 9 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Highly Scalable and Accurate Seeds for Subsequence Alignment
We propose a method for finding seeds for the local alignment of two nucleotide sequences. Our method uses randomized algorithms to find approximate seeds. We present a dynamic ...
Abhijit Pol, Tamer Kahveci
KDD
2010
ACM
252views Data Mining» more  KDD 2010»
13 years 8 months ago
Fast query execution for retrieval models based on path-constrained random walks
Many recommendation and retrieval tasks can be represented as proximity queries on a labeled directed graph, with typed nodes representing documents, terms, and metadata, and labe...
Ni Lao, William W. Cohen
BMCBI
2006
131views more  BMCBI 2006»
13 years 4 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...