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» Approximate Similarity Search in Genomic Sequence Databases ...
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BMCBI
2006
112views more  BMCBI 2006»
13 years 5 months ago
A phylogenomic gene cluster resource: the Phylogenetically Inferred Groups (PhIGs) database
Background: We present here the PhIGs database, a phylogenomic resource for sequenced genomes. Although many methods exist for clustering gene families, very few attempt to create...
Paramvir S. Dehal, Jeffrey L. Boore
BMCBI
2006
129views more  BMCBI 2006»
13 years 5 months ago
Fast index based algorithms and software for matching position specific scoring matrices
Background: In biological sequence analysis, position specific scoring matrices (PSSMs) are widely used to represent sequence motifs in nucleotide as well as amino acid sequences....
Michael Beckstette, Robert Homann, Robert Giegeric...
BMCBI
2006
143views more  BMCBI 2006»
13 years 5 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
NAR
2006
75views more  NAR 2006»
13 years 5 months ago
OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups
The OrthoMCL database (http://orthomcl.cbil.upenn. edu) houses ortholog group predictions for 55 spe10 cies, including 16 bacterial and 4 archaeal genomes representing phylogeneti...
Feng Chen, Aaron J. Mackey, Christian J. Stoeckert...
SIGMOD
2011
ACM
150views Database» more  SIGMOD 2011»
12 years 8 months ago
WHAM: a high-throughput sequence alignment method
Over the last decade the cost of producing genomic sequences has dropped dramatically due to the current so called “next-gen” sequencing methods. However, these next-gen seque...
Yinan Li, Allison Terrell, Jignesh M. Patel