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DAM
2008
116views more  DAM 2008»
13 years 5 months ago
Expected number of breakpoints after t random reversals in genomes with duplicate genes
In comparative genomics, one wishes to deduce the evolutionary distance between dierent species by studying their genomes. Using gene order information, we seek the number of time...
Niklas Eriksen
CPM
1999
Springer
129views Combinatorics» more  CPM 1999»
13 years 9 months ago
On the Structure of Syntenic Distance
This paper examines some of the rich structure of the syntenic distance model of evolutionary distance, introduced by Ferretti et al. (1996). The syntenic distance between two gen...
David Liben-Nowell
TAMC
2009
Springer
13 years 11 months ago
Approximability and Fixed-Parameter Tractability for the Exemplar Genomic Distance Problems
In this paper, we present a survey of the approximability and fixed-parameter tractability results for some Exemplar Genomic Distance problems. We mainly focus on three problems: ...
Binhai Zhu
FSTTCS
2003
Springer
13 years 10 months ago
Comparing Sequences with Segment Rearrangements
Computational genomics involves comparing sequences based on “similarity” for detecting evolutionary and functional relationships. Until very recently, available portions of th...
Funda Ergün, S. Muthukrishnan, Süleyman ...
BIOINFORMATICS
2011
13 years 8 days ago
Algorithms for sorting unsigned linear genomes by the DCJ operations
Motivation: The double cut and join operation (abbreviated as DCJ) has been extensively used for genomic rearrangement. Although the DCJ distance between signed genomes with both ...
Haitao Jiang, Binhai Zhu, Daming Zhu