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JCO
2008
76views more  JCO 2008»
13 years 6 months ago
On the inapproximability of the exemplar conserved interval distance problem of genomes
In this paper we present two main results about the inapproximability of the exemplar conserved interval distance problem of genomes. First, we prove that it is NP-complete to deci...
Zhixiang Chen, Richard H. Fowler, Bin Fu, Binhai Z...
ICALP
2009
Springer
14 years 6 months ago
Correlation Clustering Revisited: The "True" Cost of Error Minimization Problems
Correlation Clustering was defined by Bansal, Blum, and Chawla as the problem of clustering a set of elements based on a possibly inconsistent binary similarity function between e...
Nir Ailon, Edo Liberty
COCOON
2003
Springer
13 years 11 months ago
Genomic Distances under Deletions and Insertions
As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome ev...
Mark Marron, Krister M. Swenson, Bernard M. E. Mor...
BMCBI
2005
93views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2006
192views more  BMCBI 2006»
13 years 6 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...