In this paper we present two main results about the inapproximability of the exemplar conserved interval distance problem of genomes. First, we prove that it is NP-complete to deci...
Zhixiang Chen, Richard H. Fowler, Bin Fu, Binhai Z...
Correlation Clustering was defined by Bansal, Blum, and Chawla as the problem of clustering a set of elements based on a possibly inconsistent binary similarity function between e...
As more and more genomes are sequenced, evolutionary biologists are becoming increasingly interested in evolution at the level of whole genomes, in scenarios in which the genome ev...
Mark Marron, Krister M. Swenson, Bernard M. E. Mor...
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...