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» Assembly complexity of prokaryotic genomes using short reads
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FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 3 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
BMCBI
2011
13 years 24 days ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
BMCBI
2010
161views more  BMCBI 2010»
13 years 3 months ago
LTC: a novel algorithm to improve the efficiency of contig assembly for physical mapping in complex genomes
Background: Physical maps are the substrate of genome sequencing and map-based cloning and their construction relies on the accurate assembly of BAC clones into large contigs that...
Zeev Frenkel, Etienne Paux, David I. Mester, Cathe...
AC
2004
Springer
13 years 5 months ago
Shotgun Sequence Assembly
Shotgun sequencing is the most widely used technique for determining the DNA sequence of organisms. It involves breaking up the DNA into many small pieces that can be read by auto...
Mihai Pop
BMCBI
2010
189views more  BMCBI 2010»
13 years 5 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...