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» Assembly of Large Genomes from Paired Short Reads
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BMCBI
2006
122views more  BMCBI 2006»
13 years 6 months ago
PET-Tool: a software suite for comprehensive processing and managing of Paired-End diTag (PET) sequence data
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
Kuo Ping Chiu, Chee-Hong Wong, Qiongyu Chen, Prami...
BMCBI
2007
123views more  BMCBI 2007»
13 years 6 months ago
Tracembler - software for in-silico chromosome walking in unassembled genomes
Background: Whole genome shotgun sequencing produces increasingly higher coverage of a genome with random sequence reads. Progressive whole genome assembly and eventual finishing ...
Qunfeng Dong, Matthew D. Wilkerson, Volker Brendel
BMCBI
2005
115views more  BMCBI 2005»
13 years 6 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
SCFBM
2008
91views more  SCFBM 2008»
13 years 5 months ago
Simple tools for assembling and searching high-density picolitre pyrophosphate sequence data
Background: The advent of pyrophosphate sequencing makes large volumes of sequencing data available at a lower cost than previously possible. However, the short read lengths are d...
Nicolas J. Parker, Andrew G. Parker
AC
2004
Springer
13 years 6 months ago
Shotgun Sequence Assembly
Shotgun sequencing is the most widely used technique for determining the DNA sequence of organisms. It involves breaking up the DNA into many small pieces that can be read by auto...
Mihai Pop