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BMCBI
2010
105views more  BMCBI 2010»
13 years 5 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
ECTEL
2007
Springer
13 years 11 months ago
Scruffy Technologies to Enable (Work-integrated) Learning
Abstract. The goal of the APOSDLE (Advanced Process-Oriented SelfDirected Learning environment) project is to support work-integrated learning of knowledge workers. We argue that w...
Stefanie N. Lindstaedt, Peter Scheir, Armin Ulbric...
ICDE
2010
IEEE
222views Database» more  ICDE 2010»
13 years 3 months ago
Finding Clusters in subspaces of very large, multi-dimensional datasets
Abstract— We propose the Multi-resolution Correlation Cluster detection (MrCC), a novel, scalable method to detect correlation clusters able to analyze dimensional data in the ra...
Robson Leonardo Ferreira Cordeiro, Agma J. M. Trai...
ICFP
2010
ACM
13 years 6 months ago
Logical types for untyped languages
Programmers reason about their programs using a wide variety of formal and informal methods. Programmers in untyped languages such as Scheme or Erlang are able to use any such met...
Sam Tobin-Hochstadt, Matthias Felleisen
WSDM
2010
ACM
160views Data Mining» more  WSDM 2010»
14 years 2 months ago
Learning Concept Importance Using a Weighted Dependence Model
Modeling query concepts through term dependencies has been shown to have a significant positive effect on retrieval performance, especially for tasks such as web search, where rel...
Michael Bendersky, Donald Metzler, W. Bruce Croft