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BMCBI
2005
113views more  BMCBI 2005»
13 years 6 months ago
Systematic survey reveals general applicability of "guilt-by-association" within gene coexpression networks
Background: Biological processes are carried out by coordinated modules of interacting molecules. As clustering methods demonstrate that genes with similar expression display incr...
Cecily J. Wolfe, Isaac S. Kohane, Atul J. Butte
BMCBI
2006
108views more  BMCBI 2006»
13 years 6 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2006
146views more  BMCBI 2006»
13 years 6 months ago
GeneTools - application for functional annotation and statistical hypothesis testing
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Vidar Beisvag, Frode K. R. Jünge, Hallgeir Be...
NAR
2002
138views more  NAR 2002»
13 years 5 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...
BMCBI
2010
154views more  BMCBI 2010»
13 years 3 months ago
Knowledge-based matrix factorization temporally resolves the cellular responses to IL-6 stimulation
Background: External stimulations of cells by hormones, cytokines or growth factors activate signal transduction pathways that subsequently induce a re-arrangement of cellular gen...
Andreas Kowarsch, Florian Blöchl, Sebastian B...