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» Assessing protein similarity with Gene Ontology and its use ...
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BMCBI
2004
144views more  BMCBI 2004»
13 years 4 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 10 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BMCBI
2010
122views more  BMCBI 2010»
12 years 11 months ago
Functional enrichment analyses and construction of functional similarity networks with high confidence function prediction by PF
Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Troy Hawkins, Meghana Chitale, Daisuke Kihara
NAR
2007
260views more  NAR 2007»
13 years 3 months ago
WoLF PSORT: protein localization predictor
WoLF PSORT is an extension of the PSORT II program for protein subcellular location prediction. WoLF PSORT converts protein amino acid sequences into numerical localization featur...
Paul Horton, Keun-Joon Park, Takeshi Obayashi, Nao...
BMCBI
2008
200views more  BMCBI 2008»
13 years 4 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia