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BMCBI
2006
183views more  BMCBI 2006»
13 years 6 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
BMCBI
2010
183views more  BMCBI 2010»
13 years 3 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2010
160views more  BMCBI 2010»
13 years 6 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
CIKM
2010
Springer
13 years 4 months ago
A hierarchical approach to reachability query answering in very large graph databases
The cost of reachability query computation using traditional algorithms such as depth first search or transitive closure has been found to be prohibitive and unacceptable in mass...
Saikat K. Dey, Hasan M. Jamil
BIOINFORMATICS
2006
142views more  BIOINFORMATICS 2006»
13 years 6 months ago
Intervention in a family of Boolean networks
Motivation: Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied...
Ashish Choudhary, Aniruddha Datta, Michael L. Bitt...