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IJBRA
2006
59views more  IJBRA 2006»
13 years 5 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2005
114views more  BMCBI 2005»
13 years 5 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
IV
2008
IEEE
296views Visualization» more  IV 2008»
14 years 1 days ago
Revealing Subnetwork Roles using Contextual Visualization: Comparison of Metabolic Networks
This article is addressing a recurrent problem in biology: mining newly built large scale networks. Our approach consists in comparing these new networks to well known ones. The v...
Romain Bourqui, Fabien Jourdan
BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
Extending pathways based on gene lists using InterPro domain signatures
Background: High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly...
Florian Hahne, Alexander Mehrle, Dorit Arlt, Annem...
BMCBI
2005
152views more  BMCBI 2005»
13 years 5 months ago
CoPub Mapper: mining MEDLINE based on search term co-publication
Background: High throughput microarray analyses result in many differentially expressed genes that are potentially responsible for the biological process of interest. In order to ...
Blaise T. F. Alako, Antoine Veldhoven, Sjozef van ...