Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
BTO, the BRENDA Tissue Ontology (http://www .BTO.brenda-enzymes.org) represents a comprehensive structured encyclopedia of tissue terms. The project started in 2003 to create a co...
Marion Gremse, Antje Chang, Ida Schomburg, Andreas...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
—With the development of improved and cost-effective technologies, it is now possible to detect thousands of metabolites in biofluids or specific organs, and reliably quantify th...
Ali Cakmak, Arun Dsouza, Richard Hanson, Gultekin ...