Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...