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BMCBI
2011
12 years 8 months ago
A Simple Approach to Ranking Differentially Expressed Gene Expression Time Courses through Gaussian Process Regression
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
Alfredo A. Kalaitzis, Neil D. Lawrence
RECOMB
2010
Springer
13 years 11 months ago
Hierarchical Generative Biclustering for MicroRNA Expression Analysis
Clustering methods are a useful and common first step in gene expression studies, but the results may be hard to interpret. We bring in explicitly an indicator of which genes tie ...
José Caldas, Samuel Kaski
BMCBI
2008
171views more  BMCBI 2008»
13 years 4 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
BMCBI
2010
118views more  BMCBI 2010»
13 years 4 months ago
Identifying differentially regulated subnetworks from phosphoproteomic data
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
BMCBI
2006
147views more  BMCBI 2006»
13 years 4 months ago
A case study in pathway knowledgebase verification
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...
Stephen A. Racunas, Nigam Shah, Nina V. Fedoroff